Sodium Fumarate
AKA “7704-73-6, mafusol, Fumaric acid, sodium salt, F11949924I, 2-Butenedioic acid (E)-, E365, RefChem:183892, DTXSID10227847, 227-535-4
Ingredient
Ingredient Facts
Sodium fumarate
AKA: 7704-73-6, Mafusol, Fumaric acid, Sodium salt, F11949924I, 2-Butenedioic acid (E)-, E365, RefChem:183892, DTXSID10227847, 227-535-4
Ingredient · Buffering · EWG: 4
Synthetic
Not Clean
Fumaric acid is a precursor to L-malate in the Krebs tricarboxylic acid cycle. It is formed by the oxidation of succinate by succinate dehydrogenase. Fumarate is converted by fumarase to malate. A fumarate is a salt or ester of the organic compound fumaric acid, a dicarboxylic acid. Fumarate has recently been recognized as an oncometabolite. (A15199). As a food additive, fumaric acid is used to impart a tart taste to processed foods. It is also used as an antifungal agent in boxed foods such as cake mixes and flours, as well as tortillas. Fumaric acid is also added to bread to increase the porosity of the final baked product. It is used to impart a sour taste to sourdough and rye bread. In cake mixes, it is used to maintain a low pH and prevent clumping of the flours used in the mix. In fruit drinks, fumaric acid is used to maintain a low pH which, in turn, helps to stabilize flavor and color. Fumaric acid also prevents the growth of E. coli in beverages when used in combination with s
Formula
C4H3NaO4
Mol. Weight
138.05
CAS #
5873-57-4, 7704-73-6
Form
Powder
State
Solid; [Sigma-Aldrich MSDS]
See origin →
Functions
Buffering
Anti-Inflammatory
Antimicrobial
Fights Acne
Maintains optimal pH
Traditional Use
A modern ingredient derived from fumaric acid chemistry, developed in the 20th century. Used in cosmetics as a preservative and buffering agent, though not rooted in traditional medicine or skincare.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Non-Comedogenic
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
Final Report on the Safety Assessment of Fumaric Acid and Related Salts and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Disodium Fumarate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Fumaric Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sodium Fumarate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Fumaric Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR