Sodium Palmitoyl Proline
AKA “UNII-64L053FRFO, Sodium 5-oxo-1-palmitoyl-L-prolinate, N-Palmitoyl-L-proline sodium salt, EINECS 261-406-3, SODIUM PALMITOYL PROLINE [WHO-DD], RefChem:184056, SODIUM PALMITOYL PROLINE [INCI]
Synthetic
Ingredient Facts
Sodium palmitoyl proline
AKA: UNII-64L053FRFO, Sodium 5-oxo-1-palmitoyl-L-prolinate, N-Palmitoyl-L-proline sodium salt, EINECS 261-406-3, SODIUM PALMITOYL PROLINE [WHO-DD], RefChem:184056, SODIUM PALMITOYL PROLINE [INCI]
Synthetic · Humectant · EWG: 4
Synthetic
Humectant
Occlusive
Skin Conditioner
Amino Acid
Synthetic
Clean
A gentle amino acid derivative that softens and smooths hair and skin, helping products feel luxurious and moisturized.
Formula
C21H38NNaO3
Mol. Weight
375.50
CAS #
58725-33-0
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Conditions Skin
Softens & Smooths
Traditional Use
Unable to provide traditional use description without a valid INCI or common name; this appears to be a CAS number without corresponding ingredient information.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
EWG
4
CIR
Insufficient
Pregnancy
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USAunder review
CANADApermitted
Regulatory Agencies
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR