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Sodium Palmitoyl Sarcosinate
AKA “4028-10-8, N-Palmitoylsarcosine sodium, sodium N-palmitoylsarcosinate, SARCOSINATE PN, 7297LY09YF, sodium palmitoylsarcosinate, NIKKOL SARCOSINATE P, NIKKOL SARCOSINATE PN, Glycine, N-methyl-N-(1-oxohexadecyl)-, sodium salt”
Surfactant
Ingredient Facts
Sodium palmitoyl sarcosinate
AKA: 4028-10-8, N-Palmitoylsarcosine sodium, Sodium N-palmitoylsarcosinate, SARCOSINATE PN, 7297LY09YF, Sodium palmitoylsarcosinate, NIKKOL SARCOSINATE P, NIKKOL SARCOSINATE PN, Glycine, N-methyl-N-(1-oxohexadecyl)-, Sodium salt
Surfactant · Cleansing · EWG: 1
Synthetic
Cleanser
Skin Conditioner
Hair Care
Amino Acid
Plant Oil
Clean
Sodium N-methyl-N-(1-oxohexadecyl)aminoacetate
Formula
C19H36NNaO3
Mol. Weight
349.50
CAS #
4028-10-8
Form
Liquid
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Surfactant Cleansing
Anti-Inflammatory
Antimicrobial
Fights Acne
Removes dirt and impurities
Lifts away dirt and oil
Softens and detangles hair
Traditional Use
Developed in the mid-20th century as a mild amino acid-based surfactant derived from palm oil. Created to provide gentler cleansing than traditional soaps.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
Industry Max
Industry typically uses up to 4.0% in leave-on products (217 products reported). Source: CIR Safety Assessment (CIR Seq 607).
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Capryloyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Flower/Leaf/Stem Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Cell Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Conditioned Media
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Polypeptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Pulp
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcoat Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Flour
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Germ Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Hull
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Peptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sterols
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Palmitoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium Palmitoyl Sarcosinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Undecylenoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Capryloyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soy) Peptides
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Flour
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Germ Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Oil Unsaponifiables
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Phytoplacenta Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sprout Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sterols
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja Soybean Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Palmitoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Palmitoyl Sarcosinate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Undecylenoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Capryloyl glycine: A polyfunctional cosmetic ingredient and potential skin sensitizer.
Mangodt EA, Dendooven E, De Fré C, Lambert J, Aerts O
Contact dermatitis, 2019
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR