Sodium PCA
AKA “Sodium L-pyroglutamate, Sodium pyroglutamate, Sodium pidolate, L-Proline, monosodium salt, L-5-Oxoproline monosodium salt, Sodium pyrrolidone-5-carboxylate, 5-Oxo-L-proline monosodium salt
Synthetic
vote to see if the hive agrees
Ingredient Facts
Sodium pca
AKA: Sodium L-pyroglutamate, Sodium pyroglutamate, Sodium pidolate, L-Proline, Monosodium salt, L-5-Oxoproline monosodium salt, Sodium pyrrolidone-5-carboxylate, 5-Oxo-L-proline monosodium salt
Synthetic · Antistatic | Hair Conditioning | Humectant | Skin Conditioning · EWG: 4
Plant-Derived
Humectant
Skin Conditioner
Hair Care
Amino Acid
Synthetic
Clean
A naturally derived humectant that hydrates skin and hair while reducing frizz and static. Helps lock in moisture for a softer, smoother feel.
Formula
C5H6NNaO3
Mol. Weight
151.10
CAS #
28874-51-3
Form
Liquid
Plant-Derived
Synthetic. Derived from L-pyroglutamic acid, a naturally occurring amino acid derivative within the pyroglutamate chemical family. Synthesized through acetylation and sodium salt formation of pyroglutamic acid precursors.
Function
Antistatic | Hair Conditioning | Humectant | Skin Conditioning
Benefits
Locks In Moisture
Traditional Use
Sodium PCA is the salt form of pyrrolidone carboxylic acid, a natural humectant found in human skin. Identified in the 1970s as a key component of the skin's natural moisture factor and incorporated into moisturizers to mimic skin's natural hydration mechanism.
Skin Types
all-skin-types
Best For
Target
Dryness
Melanin-Rich Skin
Suitable
Pregnancy Safe
Yes
EWG Score4
CIR Safety Findings
all-shades-safe, Not a Sensitizer
Concentration Guide
Industry Max
Industry typically uses up to 2.5% in leave-on products (84 products reported). Dermal absorption: 5%. Source: CIR Safety Assessment (CIR Seq 683).
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR