Sodium Xylenesulfonate
AKA “Naxonate, Hydrotrope, Xylenesulfonic Acid Sodium Salt, Stepanate X, Naxonate G, Richonate SXS, Cyclophil sxs30, Conco SXS, Surco SXS”
Surfactant
Ingredient Facts
Sodium xylenesulfonate
AKA: Naxonate, Hydrotrope, Xylenesulfonic Acid Sodium Salt, Stepanate X, Naxonate G, Richonate SXS, Cyclophil sxs30, Conco SXS, Surco SXS
Surfactant · Hydrotrope · EWG: 4
Synthetic
Cleanser
Not Clean
Sodium Xylenesulfonate ... safe as cosmetic ingredient in the present practice of use and concentration as described in this safety assessment, when formulated to be nonirritating
Solubility greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
Formula
C8H9NaO3S
Mol. Weight
208.21
CAS #
1300-72-7
Form
Liquid
State
Xylenesulfonic acid, sodium salt is an odorless white crystalline powder. (NTP, 1992)
See origin →
Functions
Hydrotrope
Surfactant Hydrotrope
Locks In Moisture
Improves ingredient solubility
Traditional Use
A synthetic aromatic sulfonate developed in the 20th century for use as a solubilizing agent and surfactant in cosmetics. It has no traditional use history and was created specifically for modern cosmetic chemistry applications.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Safety assessment of xylene sulfonic acid, toluene sulfonic acid, and alkyl aryl sulfonate hydrotropes as used in cosmetics.
Bergfeld WF, Belsito DV, Klaassen CD, Hill R, Liebler D et al.
International journal of toxicology, 2011
Safety assessment of xylene sulfonic acid, toluene sulfonic acid, and alkyl aryl sulfonate hydrotropes as used in cosmetics.
Bergfeld WF, Belsito DV, Klaassen CD, Hill R, Liebler D et al.
International journal of toxicology, 2011
Safety Assessment of Xylene Sulfonic Acid, Toluene Sulfonic Acid, and Alkyl Aryl Sulfonate Hydrotropes as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium Xylenesulfonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
NTP Toxicology and Carcinogenesis Studies of Technical Grade Sodium Xylenesulfonate (CAS No. 1300-72-7) in F344/N Rats and B6C3F1 Mice (Dermal Studies
National Toxicology Program
National Toxicology Program technical report series, 1998
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR