Stearic Hydrazide
AKA “Stearic acid hydrazide, 4130-54-5, Octadecanoic acid, hydrazide, Stearic acid, UNII-3FV1C68XOP, 3FV1C68XOP, EINECS 223-946-8, NSC 67213, NSC-67213
Ingredient
Ingredient Facts
Stearic hydrazide
AKA: Stearic acid hydrazide, 4130-54-5, Octadecanoic acid, Stearic acid, UNII-3FV1C68XOP, 3FV1C68XOP, EINECS 223-946-8, NSC 67213, NSC-67213
Ingredient · Not Reported · EWG: 4
Plant-Derived
Not Clean
The safety of Stearic Hydrazide has not been documented and substantiated. The CIR Expert Panel cannot conclude that this ingredient is safe for use in cosmetic products until the appropriate safety data have been obtained and evaluated.
Formula
C18H38N2O
Mol. Weight
298.50
CAS #
4130-54-5
Form
Powder
See origin →
Functions
Not Reported
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Traditional Use
A synthetic derivative of stearic acid developed in the 20th century for cosmetic and industrial applications. Created primarily as a blowing agent and chemical intermediate with no traditional use history.
Skin Types
all-skin-types
Best For
General
EWG
4
CIR
Safe as used
Pregnancy
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Amended Final Report on the Safety Assessment of Hydroxystearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Adipic Acid Dihydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Isostearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Stearic Hydrazide
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report: Safety Assessment of Polyhydroxystearic Acid, Poly(3-Hydroxyoctanoic Acid, and Polylactic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Re-evaluation: Safety Assessment of Hydroxystearic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
10-Hydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Polyhydroxystearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Stearic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isostearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Polyhydroxystearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Stearic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Hydrazides and their salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Simultaneous contact sensitivity to hydroxystearic acid and C18-36 acid triglyceride in lip glosses.
Kimura M, Kawada A, Ogino M, Murayama Y
Contact dermatitis, 2002
Microemulsions based on TPGS and isostearic acid for imiquimod formulation and skin delivery.
Pescina S, Garrastazu G, Del Favero E, Rondelli V, Cantù L et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Bio-derived hydroxystearic acid ameliorates skin age spots and conspicuous pores.
Schütz R, Rawlings AV, Wandeler E, Jackson E, Trevisan S et al.
International journal of cosmetic science, 2019
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR