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Stearoyl Sarcosine
AKA “142-48-3, n-stearoylsarcosine, Glycine, N-methyl-N-(1-oxooctadecyl)-, UNII-AJ0EI4K4R8, AJ0EI4K4R8, SARKOSYL S, Stearoyl N-methylaminoacetic acid, Stearoyl N-methylglycine, EINECS 205-539-7”
Surfactant
Ingredient Facts
Stearoyl sarcosine
AKA: 142-48-3, N-stearoylsarcosine, Glycine, N-methyl-N-(1-oxooctadecyl)-, UNII-AJ0EI4K4R8, AJ0EI4K4R8, SARKOSYL S, Stearoyl N-methylaminoacetic acid, Stearoyl N-methylglycine, EINECS 205-539-7
Surfactant · Cleansing · EWG: 4
Plant-Derived
Cleanser
Skin Conditioner
Hair Care
Plant Oil
Not Clean
The CIR Expert Panel concluded that the following ingredients are safe as used in cosmetics when formulated to be non-irritating. The Expert Panel cautions that these ingredients should not be used in cosmetic products in which N-nitroso compounds can be found...Stearoyl Sarcosine...
Formula
C21H41NO3
Mol. Weight
355.60
CAS #
142-48-3
Form
Liquid
See origin →
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Surfactant Cleansing
Antimicrobial
Fights Acne
Antioxidant
Removes dirt and impurities
Lifts away dirt and oil
Reduces flyaways
Softens and detangles hair
Traditional Use
Synthesized in the mid-20th century as a mild surfactant and conditioning agent. Designed to provide gentle cleansing while maintaining skin hydration in contemporary cosmetics.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
Industry Max
Industry typically uses up to 4.0% in leave-on products (217 products reported). Source: CIR Safety Assessment (CIR Seq 607).
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Final Report on the Safety Assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium M
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Capryloyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Flower/Leaf/Stem Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Cell Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Conditioned Media
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Polypeptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Pulp
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcoat Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Flour
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Germ Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Hull
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Peptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sterols
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Palmitoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Stearoyl Sarcosine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Undecylenoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Capryloyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soy) Peptides
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Flour
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Germ Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Oil Unsaponifiables
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Phytoplacenta Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sprout Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sterols
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja Soybean Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Palmitoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Undecylenoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl
Lanigan RS
International journal of toxicology, 2001
→
Capryloyl glycine: A polyfunctional cosmetic ingredient and potential skin sensitizer.
Mangodt EA, Dendooven E, De Fré C, Lambert J, Aerts O
Contact dermatitis, 2019
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR