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Sucrose Acetate Isobutyrate
AKA “SAIB, Sucrose acetoisobutyrate, Saccharose acetate isobutyrate, SAIB 100S, Sucrose, diacetate hexaisobutyrate, H5KI1C3YTV, Isobutyric acid, hexaester with sucrose diacetate, INS NO.444, INS-444, alpha-D-Glucopyranoside, 6-O-acetyl-1, 3, 4-tris-O-(2-methyl-1-oxopropyl)-beta-D-fructofuranosyl, 6-acetate 2, 4-tris(2-methylpropanoate)”
Ingredient
Ingredient Facts
Sucrose acetate isobutyrate
AKA: SAIB, Sucrose acetoisobutyrate, Saccharose acetate isobutyrate, SAIB 100S, Diacetate hexaisobutyrate, H5KI1C3YTV, Isobutyric acid, Hexaester with sucrose diacetate, INS NO.444, INS-444, Alpha-D-Glucopyranoside, 6-O-acetyl-1, 3, 4-tris-O-(2-methyl-1-oxopropyl)-beta-D-fructofuranosyl, 6-acetate 2, 4-tris(2-methylpropanoate)
Ingredient · Film Forming · EWG: 2
Plant-Derived
Occlusive
Clean
Sucrose di(acetate) hexaisobutyrate
Formula
C40H62O19
Mol. Weight
846.90
CAS #
126-13-6
Form
Powder
See origin →
Functions
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Plasticiser
Anti-Aging
Antioxidant
Anti-Inflammatory
Creates protective layer
Adds flexibility
Traditional Use
Developed in the mid-20th century as a synthetic ester derived from sucrose and fatty acids. Used in cosmetics as a film-former and binder to improve product texture and adherence, particularly in color cosmetics and hair care formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Sucrose cocoate, a component of cosmetic preparations, enhances nasal and ocular peptide absorption.
Ahsan F, Arnold JJ, Meezan E, Pillion DJ
International journal of pharmaceutics, 2003
→
Punica Granatum Fruit/Sucrose Ferment Filtrate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Acetate Isobutyrate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Acetate/Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Benzoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Dilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Hexaerucate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Hexaoleate/Hexapalmitate/Hexastearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Hexapalmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Octaacetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Palmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Pentaerucate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Pentahydroxystearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polybehenate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polycottonseedate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polylaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polylinoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polyoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polysoyate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Polystearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Tetrahydroxystearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Tetraisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Tribehenate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Trilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sucrose Tristearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
A peculiar case of sensitization to Candelilla Cera and sucrose (di)stearate in a toddler.
Darrigade AS, Dendooven E, Mangodt E, Vermander E, Hagendorens M et al.
Contact dermatitis, 2020
→
Sucrose
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Acetate Isobutyrate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Acetate/Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Benzoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Dilaurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Distearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Myristate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Octaacetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Palmitate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Polycottonseedate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Polysoyate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Polystearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Tetraisostearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Tetrastearate Triacetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Trilaurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sucrose Tristearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
A Potential Role of Keratinocyte-Derived Bilirubin in Human Skin Yellowness and Its Amelioration by Sucrose Laurate/Dilaurate.
Fang B, Card PD, Chen J, Li L, Laughlin T et al.
International journal of molecular sciences, 2022
→
A Potential Role of Keratinocyte-Derived Bilirubin in Human Skin Yellowness and Its Amelioration by Sucrose Laurate/Dilaurate.
Fang B, Card PD, Chen J, Li L, Laughlin T et al.
International journal of molecular sciences, 2022
→
The Effect of Alkyl Chain Number in Sucrose Surfactant on the Physical Properties of Quercetin-Loaded Deformable Nanoliposome and Its Effect on In Vit
Hong IK, Ha JH, Han S, Kang H, Park SN
Nanomaterials (Basel, Switzerland), 2018
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Development of sucrose stearate-based nanoemulsions and optimisation through γ-cyclodextrin.
Klang V, Matsko N, Raupach K, El-Hagin N, Valenta C
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2011
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Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsions.
Klang V, Matsko N, Zimmermann AM, Vojnikovic E, Valenta C
International journal of pharmaceutics, 2010
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Enhancement of stability and skin permeation by sucrose stearate and cyclodextrins in progesterone nanoemulsions.
Klang V, Matsko N, Zimmermann AM, Vojnikovic E, Valenta C
International journal of pharmaceutics, 2010
→
Allergic contact dermatitis to sucrose stearate in a facial moisturizing cream.
Raison-Peyron N, Aerts O, Dereure O
Contact dermatitis, 2020
→
Prominent efficiency in skin delivery of resveratrol by novel sucrose oleate microemulsion.
Yutani R, Komori Y, Takeuchi A, Teraoka R, Kitagawa S
The Journal of pharmacy and pharmacology, 2016
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR