t-Butyl Acetate
AKA “TERT-BUTYL ACETATE, 540-88-5, Acetic acid, 1, 1-dimethylethyl ester, Texaco lead appreciator, tert-butyl ester, 1-Dimethyl acetate, 76N22HKP3X, DTXSID1022055, NSC-59719”
Ingredient
Ingredient Facts
T-butyl acetate
AKA: TERT-BUTYL ACETATE, 540-88-5, Acetic acid, 1, 1-dimethylethyl ester, Texaco lead appreciator, Tert-butyl ester, 1-Dimethyl acetate, 76N22HKP3X, DTXSID1022055, NSC-59719
Ingredient · Solvent · EWG: 1
Synthetic
Solvent
Clean
Tert-butyl acetate is a colorless liquid with a mild odor. Floats on water. Produces irritating vapor. (USCG, 1999)
Solubility Insoluble (NIOSH, 2024)
Formula
C6H12O2
Mol. Weight
116.16
CAS #
540-88-5
Form
Liquid
State
Tert-butyl acetate is a colorless liquid with a mild odor. Floats on water. Produces irritating vapor. (USCG, 1999)
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
A synthetic organic solvent derived from petroleum, developed in the 20th century for use in nail polish, lacquers, and other cosmetic formulations requiring volatile organic solvents.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Acetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
dehydroacetic acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
t-Butyl Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
dehydroacetic acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
t-Butyl Acetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.
Fujii MY, Asakawa Y, Fukami T
International journal of pharmaceutics, 2020
Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice.
Fukami H, Tachimoto H, Kishi M, Kaga T, Waki H et al.
Journal of lipid research, 2010
Trichloroacetic acid
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR