Tocophersolan
AKA “DTXSID50860035, 2-Hydroxyethyl 2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-3, 4-dihydro-2H-1-benzopyran-6-yl butanedioate, RefChem:1063424, DTXCID30210296, 30999-06-5, Tocophersolan [USAN], Vitamin E TPGS, Tocofersolan (INN), Tocophersolan (USAN), 1-O-(2-hydroxyethyl) 4-O-[2, 4-dihydrochromen-6-yl] butanedioate
Antioxidant
Ingredient Facts
Tocophersolan
AKA: DTXSID50860035, 2-Hydroxyethyl 2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-3, 4-dihydro-2H-1-benzopyran-6-yl butanedioate, RefChem:1063424, DTXCID30210296, 30999-06-5, Tocophersolan [USAN], Vitamin E TPGS, Tocofersolan (INN), Tocophersolan (USAN), 1-O-(2-hydroxyethyl) 4-O-[2, 4-dihydrochromen-6-yl] butanedioate
Antioxidant · Antioxidant · EWG: 1
Synthetic
Antioxidant
Clean
Butanedioic acid, mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecy)-2H-1-benzopyran-6-yl] ester, polymer with oxirane (1:22)
Effective at 0.12%
Formula
C35H58O6
Mol. Weight
574.80
CAS #
30999-06-5
Form
Liquid
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Neutralizes Free Radicals
Traditional Use
A modern water-soluble derivative of vitamin E (tocopherol) developed in the 20th century. Created to allow vitamin E's antioxidant benefits to be incorporated into water-based cosmetic formulations.
Skin Types
all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.05%
0.2%
0%0%
Effective Range
CIR reported use: 0.05-0.2
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR