Tocopheryl Phosphate
AKA “425429-22-7, DTXSID601021429, beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, compd. with 3, 4-dihydro-2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6-yl dihydrogen phosphate (1:1), I(2)-Alanine, N -(2-carboxyethyl)-N -dodecyl-, 12-trimethyltridecyl)-2H -1-benzopyran-6- yl dihydrogen phosphate (1:1)
Surfactant
Ingredient Facts
Tocopheryl phosphate
AKA: 425429-22-7, DTXSID601021429, Beta-Alanine, N-(2-carboxyethyl)-N-dodecyl-, Compd. with 3, 4-dihydro-2, 5, 7, 8-tetramethyl-2-(4, 8, 12-trimethyltridecyl)-2H-1-benzopyran-6-yl dihydrogen phosphate (1:1), I(2)-Alanine, N -(2-carboxyethyl)-N -dodecyl-, 12-trimethyltridecyl)-2H -1-benzopyran-6- yl dihydrogen phosphate (1:1)
Surfactant · Cleansing · EWG: 1
Synthetic
Cleanser
Emulsifier
Skin Conditioner
Hair Care
Plant Oil
Clean
Tocopheryl Phosphate is a complex mixture of esters of Tocopheryl (q.v.) Phosphoric Acid (q.v.)
Effective at 0.11%
Formula
C47H86NO9P
Mol. Weight
840.20
CAS #
425429-22-7
Form
Powder
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Aging
Antioxidant
Strengthens Barrier
Traditional Use
A water-soluble vitamin E derivative developed in the modern cosmetics industry. Designed to allow vitamin E's antioxidant properties to function in aqueous skincare formulations.
Skin Types
all-skin-types
Best For
Sun Damage
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.01%
0.2%
0%0%
Effective Range
CIR reported use: 0.01-0.2
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Potassium Ascorbyl Tocopheryl Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sodium Tocopheryl Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Tocopheryl Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Potassium Ascorbyl Tocopheryl Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Sodium Tocopheryl Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Tocopheryl Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR