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Tridecyl Salicylate
AKA “tridecyl 2-hydroxybenzoate, UNII-AZQ08K38Z1, VYSOL, AZQ08K38Z1, COSMACOL ESI, DERMOL TDSA, EINECS 243-214-1, Benzoic acid, 2-hydroxy-, tridecyl ester, 1-TRIDECANOL, SALICYLATE”
Synthetic
Ingredient Facts
Tridecyl salicylate
AKA: Tridecyl 2-hydroxybenzoate, UNII-AZQ08K38Z1, VYSOL, AZQ08K38Z1, COSMACOL ESI, DERMOL TDSA, EINECS 243-214-1, Benzoic acid, 2-hydroxy-, Tridecyl ester, 1-TRIDECANOL
Synthetic · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Chemical Exfoliant
Synthetic
Clean
The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Tridecyl Salicylate...
Formula
C20H32O3
Mol. Weight
320.50
CAS #
19666-16-1
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Conditions Skin
Softens & Smooths
Reduces Flyaways
Traditional Use
A synthetic UV filter and preservative developed in the mid-20th century as part of the expansion of synthetic sunscreen technology. Created to provide broad-spectrum UV protection and extend product shelf life in cosmetic formulations.
Skin Types
●all-skin-types
Best For
Sun Damage
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
Not Phototoxic
all-shades-safe
Regulatory Status
USAunder review
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Iso
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report: Safety Assessment of Benzyl Salicylate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
→
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Amyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Benzyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C12-15 Alkyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Calcium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ethylhexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexyldodecyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isocetyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isodecyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
MEA-Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Potassium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
TEA-Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Titanium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Zinc Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Amyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Butyloctyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hexyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Isodecyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
TEA-Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Tridecyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl salicylate
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
GC-MS/MS quantification of benzyl salicylate on skin and hair: A novel chemical simulant for human decontamination studies.
James T, Collins S, Amlôt R, Marczylo T
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Fragrance material review on hexyl salicylate.
Lapczynski A, Jones L, McGinty D, Bhatia S, Letizia CS et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
→
Addendum to the Scientific Opinion on Hexyl Salicylate SCCS/1658/23 (CAS/EC No. 6259-76-3/228-408-6) - Children exposure 0-3 years old
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Scientific advice – children’s exposure to Methyl salicylate (methyl 2-hydroxybenzoate) - Revision of SCCS/1654/23
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Topical delivery of salicylates.
Yeoh SC, Goh CF
Drug delivery and translational research, 2022
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR