Triisononanoin
AKA “Isodragol, XF4K22WN6T, Propane-1, 2, 3-triyl 3, 5, 5-trimethylhexanoate, DUB TING, glycerol triisononanoate, 206354-95-2, GLYCERYL TRIISONONANOATE, ISODRAGOL 660061, Isononanoic acid, 1, 3-propanetriyl ester
Skin Conditioning
Ingredient Facts
Triisononanoin
AKA: Isodragol, XF4K22WN6T, Propane-1, 2, 3-triyl 3, 5, 5-trimethylhexanoate, DUB TING, Glycerol triisononanoate, 206354-95-2, GLYCERYL TRIISONONANOATE, ISODRAGOL 660061, Isononanoic acid, 1, 3-propanetriyl ester
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Clean
Propane-1,2,3-triyl 3,5,5-trimethylhexanoate
Formula
C30H56O6
Mol. Weight
512.80
CAS #
56554-53-1, 206354-95-2
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Viscosity Controlling
Locks in moisture
Traditional Use
A synthetic triglyceride ester developed as a cosmetic emollient and conditioning agent. Created to mimic the skin-conditioning properties of natural plant oils in modern formulations.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Trilaurin, Triarachidin, Tribehenin, Tricaprin, Tricaprylin, Trierucin, Triheptanoin, Triheptylundecanoin, Triisononanoin, Triisopalmitin, Triisostearin, Trili
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Triisononanoin
European Commission
EU Cosmetic Ingredient Database (CosIng)
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
PROPANE-1
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Triisononanoin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
The Additive Influence of Propane-1,2-Diol on SDS Micellar Structure and Properties.
Gudelj M, Šurina P, Jurko L, Prkić A, Bošković P
Molecules (Basel, Switzerland), 2021
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR