Tromethamine

Tromethamine

AKA “Trometamol, Tris(Hydroxymethyl)aminomethane, Tham, Trisamine, 3-propanediol, Tris buffer, Tromethane, Tris-base”

Synthetic

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Ingredient Facts

Tromethamine

AKA: Trometamol, Tris(Hydroxymethyl)aminomethane, Trisamine, 3-propanediol, Tris buffer, Tromethane, Tris-base

Synthetic · Buffer | Fragrance · EWG: 4

Plant-Derived

Fragrance

Synthetic

Clean

Helps balance the product's pH level to keep it gentle on skin while also contributing subtle fragrance notes.

Solubility 79.1 mg/mL in ethylene glycol; 26 mg/mL in methanol; 14.6 mg/mL in anhyd ethanol; 22 mg/mL in 95% ethanol; 14 mg/mL in dimethyl formamide; 20 mg/mL in acetone; 0.5 mg/mL in ethyl acetate; 0.4 mg/mL in olive oil; 0.1 mg/mL in cyclohexane; 0.05 mg/mL in chloroform; less than 0.05 mg/mL in carbon tetrachloride

Formula

C4H11NO3

Mol. Weight

121.14

CAS #

77-86-1

Form

Liquid

Plant-Derived

Synthetic. Synthesized from ammonia and triethanolamine precursors through organic synthesis reactions. Produced via condensation and neutralization processes to create the final buffer compound.

Function

Buffer | Fragrance

Benefits

Buffering

Provides scent

Maintains optimal pH

Traditional Use

A synthetic buffering agent developed in the mid-20th century for pharmaceutical and cosmetic use. Used to stabilize pH in skincare formulations and reduce irritation from acidic or alkaline ingredients.