Tryptophan
AKA “L-tryptophan, 73-22-3, L-Tryptophane, Tryptophane, (S)-Tryptophan, trofan, tryptacin, (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid, Ardeytropin
Hair Conditioning
Ingredient Facts
Tryptophan
AKA: L-tryptophan, 73-22-3, L-Tryptophane, Tryptophane, (S)-Tryptophan, Trofan, Tryptacin, (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid, Ardeytropin
Hair Conditioning · Antistatic · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
2-Amino-3-indol-3-ylpropanoic acid
Solubility 1 to 5 mg/mL at 68 °F (NTP, 1992)
Formula
C11H12N2O2
Mol. Weight
204.22
CAS #
54-12-6, 73-22-3
Form
Powder
State
L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992)
See origin →
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Anti-Aging
Antioxidant
Anti-Inflammatory
Reduces flyaways
Softens and detangles hair
Provides scent
Traditional Use
An amino acid discovered in 1901. While not traditionally used in skincare, tryptophan has been studied in modern cosmetics for its role in protein synthesis and potential skin barrier support, though its primary historical use has been in nutrition and mental health applications.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR