Ubiquinone
AKA “Coenzyme Q10, ubidecarenone, CoQ10, ubiquinone-10, Ubiquinone 50, Ubiquinone 10, Ubiquinone Q10, Ubidecarenona”
Synthetic
Ingredient Facts
Ubiquinone
AKA: Coenzyme Q10, Ubidecarenone, CoQ10, Ubiquinone-10, Ubiquinone 50, Ubiquinone 10, Ubiquinone Q10, Ubidecarenona
Synthetic · Antioxidant · EWG: 3
Synthetic
Antioxidant
Skin Conditioner
Synthetic
Not Clean
Ubiquinone is a cosmetic ingredient. Rated moderate hazard by EWG.
Formula
C59H90O4
Mol. Weight
863.3
CAS #
303-98-0, 1339-63-5, 60684-33-5
Form
Powder
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Neutralizes free radicals
Reduces fine lines
Traditional Use
Discovered in 1957 as a vital component of cellular energy production. Its use in skincare emerged in the 1990s when studies suggested it could reduce the appearance of fine lines and support skin cell energy production.
Skin Types
●all-skin-types
Best For
Aging
Pregnancy & Breastfeeding Safe
Yes
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Vitamins C+E+Ferulic Serum
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Gentle Retinol Night Serum
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Vitamin C Serum
Indie Lee
CoQ-10 Toner Travel
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CoQ-10 Toner
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Boosted Contouring Eye Balm
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Jump Start Smoothing Primer
Exa Beauty
Development, characterization, molecular docking, and in vivo skin penetration of coenzyme Q10 nanostructured lipid carriers using tristearin and stea
Aryani NLD, Siswodihardjo S, Soeratri W, Sari NFI
Journal of basic and clinical physiology and pharmacology, 2021
Design, optimization and characterization of coenzyme Q10- and D-panthenyl triacetate-loaded liposomes.
Çelik B, Sağıroğlu AA, Özdemir S
International journal of nanomedicine, 2017
Final Report: Safety Assessment of Ubiquinone Ingredients as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Disodium Ubiquinone
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydroxydecyl Ubiquinone
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydroxydecyl Ubiquinone
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Ubiquinone
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
The Role of Coenzyme Q10 in Skin Aging and Opportunities ...
Edward Ted Lain, Nick Agrawal, Eduardo Ruvolo, Julia M Weise, Valerie D Callender
The Journal of clinical and aesthetic dermatology, 2024
The Role of Coenzyme Q10 in Skin Aging and Opportunities ...
Edward Ted Lain, Nick Agrawal, Eduardo Ruvolo, Julia M Weise, Valerie D Callender
The Journal of clinical and aesthetic dermatology, 2024
The Role of Coenzyme Q10 in Skin Aging and Opportunities ...
Edward Ted Lain, Nick Agrawal, Eduardo Ruvolo, Julia M Weise, Valerie D Callender
The Journal of clinical and aesthetic dermatology, 2024
Allergic contact dermatitis to hydroxydecyl ubiquinone (idebenone) following application of anti-ageing cosmetic cream.
Mc Aleer MA, Collins P
Contact dermatitis, 2008
Investigation of ex vivo Skin Penetration of Coenzyme Q10 from Microemulsions and Hydrophilic Cream.
Tessema EN, Bosse K, Wohlrab J, Mrestani Y, Neubert RHH
Skin pharmacology and physiology, 2020
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR