Xylityl Sesquicaprylate
AKA “Xylityl 1-caprylate, NYE7YKH9FT, 181632-90-6, RefChem:1101094, Xylitol, 1-octanoate, UNII-NYE7YKH9FT, DTXSID401371375
Surfactant
Ingredient Facts
Xylityl sesquicaprylate
AKA: Xylityl 1-caprylate, NYE7YKH9FT, 181632-90-6, RefChem:1101094, Xylitol, 1-octanoate, UNII-NYE7YKH9FT, DTXSID401371375
Surfactant · Antimicrobial · EWG: 4
Synthetic
Humectant
Preservative
Cleanser
Emulsifier
Skin Conditioner
Not Clean
Xylityl Sesquicaprylate is a mixture of mono- and diesters of Caprylic Acid and the hexitol anhydrides derived from Xylitol.
Formula
C13H26O6
Mol. Weight
278.34
CAS #
181632-90-6
See origin →
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Deodorant
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Locks In Moisture
Traditional Use
Developed in the late 20th century as a synthetic emollient derived from xylitol. Designed to provide lightweight hydration and smooth application in skincare and cosmetic formulations.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
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Are sodium lauryl sulfate-containing toothpastes suitable vehicles for xylitol?
Assev S, Wåler SM, Rølla G
European journal of oral sciences, 1997
Are sodium lauryl sulfate-containing toothpastes suitable vehicles for xylitol?
Assev S, Wåler SM, Rølla G
European journal of oral sciences, 1997
Safety Assessment of Mannitol, Sorbitol, and Xylitol as U...
Priya Cherian, Wilma F Bergfeld, Donald V Belsito, Curtis D Klaassen, Daniel C Liebler, James G Marks + 6 more
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose,Anhydroglucitol, Anhydroxylitol, Arabinose,Psicose, Saccharide Hydrolysate, andSaccharide Isomerate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Mannitol, Sorbitol and Xylitol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
anhydroxylitol
European Commission
EU Cosmetic Ingredient Database (CosIng)
xylitol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Xylityl Sesquicaprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
anhydroxylitol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
xylitol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Effects of Xylitol-laced Sweets on the Accumulation of Dental Plaque : A Systematic Review and Meta-Analysis.
Mostafazadehbakhtiyary M, Majidinia S, Sohouli M, Chalakinia H, Langari AS et al.
International dental journal, 2025
Xylityl Sesquicaprylate Efficacy as an Antiseptic Ingredient for Oral Care Products (Mouthwash): An In Vitro Screening Investigation against Eight Mic
Nogueira C, Mussi L, Baby AR, Zupeli R, Magalhães WV
Molecules (Basel, Switzerland), 2022
Sweeteners: erythritol, xylitol and cardiovascular risk-friend or foe?
Wölnerhanssen BK, Meyer-Gerspach AC, Arduini A, D'Alessandro A, Gronda E et al.
Cardiovascular research, 2025
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR