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Zinc Salicylate
AKA “Zinc disalicylate, 16283-36-6, zinc bis(2-hydroxybenzoate), Zinc, bis(salicylato)-, Salicylic acid, zinc salt, UNII-96OQ2F972S, DTXSID6048624, 96OQ2F972S, EINECS 240-380-7”
Ingredient
Ingredient Facts
Zinc salicylate
AKA: Zinc disalicylate, 16283-36-6, Zinc bis(2-hydroxybenzoate), Bis(salicylato)-, Salicylic acid, Zinc salt, UNII-96OQ2F972S, DTXSID6048624, 96OQ2F972S, EINECS 240-380-7
Ingredient · Antimicrobial · EWG: 4
Synthetic
Preservative
Chemical Exfoliant
Not Clean
The CIR Expert Panel concluded that the following 27 zinc salts are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating...Zinc Salicylate...
Formula
C14H10O6Zn
Mol. Weight
339.60
CAS #
16283-36-6
Form
Liquid
State
Liquid
See origin →
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Fights Bacteria
Traditional Use
A modern complex combining zinc with salicylic acid, developed in the 20th century for acne-prone skin. Created to provide both zinc's barrier support and salicylate's exfoliating benefits.
Skin Types
●all-skin-types
Best For
Acne
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
3.0%
0%4%
Reg. Limit
EU regulatory limit: 3.0%. (a) 3.0% (b) 2.0%. Not to be used for children under three years of age (11) Source: EU Cosmetics Regulation (EC) 1223/2009, Annex III (Restricted Substances), Entry 98.
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
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Salicylic Acid.
, 2006
→
Effect of a Hydrolyzed Collagen, Vitamin, and Zinc Containing Nutritional Supplement on Telogen Effluvium.
Arias EM, Manzanares S, Floriach N, Sarró E, Bravo E et al.
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Aydin Acar C, Gencer MA, Pehlivanoglu S, Yesilot S, Donmez S
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→
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Aydin Acar C, Gencer MA, Pehlivanoglu S, Yesilot S, Donmez S
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→
The role of zinc in the treatment of acne: A review of the literature.
Cervantes J, Eber AE, Perper M, Nascimento VM, Nouri K et al.
Dermatologic therapy, 2018
→
The role of zinc in the treatment of acne: A review of the literature.
Cervantes J, Eber AE, Perper M, Nascimento VM, Nouri K et al.
Dermatologic therapy, 2018
→
The role of zinc in the treatment of acne: A review of the literature.
Cervantes J, Eber AE, Perper M, Nascimento VM, Nouri K et al.
Dermatologic therapy, 2018
→
Efficacy of undecylenic acid-zinc undecylenate powder in culture positive tinea pedis.
Chretien JH, Esswein JG, Sharpe LM, Kiely JJ, Lyddon FE
International journal of dermatology, 1980
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
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Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Iso
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International journal of toxicology, 2003
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→
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International journal of toxicology, 2003
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International journal of toxicology, 2003
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Journal of animal science, 2023
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
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Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
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International journal of toxicology, 2024
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International journal of pharmaceutics, 2023
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Identification of didecyldimethylammonium salts and salicylic acid as antimicrobial compounds in commercial fermented radish kimchi.
Li J, Chaytor JL, Findlay B, McMullen LM, Smith DC et al.
Journal of agricultural and food chemistry, 2015
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Identification of didecyldimethylammonium salts and salicylic acid as antimicrobial compounds in commercial fermented radish kimchi.
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Identification of didecyldimethylammonium salts and salicylic acid as antimicrobial compounds in commercial fermented radish kimchi.
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Liu H, Yu H, Xia J, Liu L, Liu GJ et al.
The Cochrane database of systematic reviews, 2020
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Targeted Delivery of Zinc Pyrithione to Skin Epithelia.
Sean E Mangion, Amy M Holmes, Michael S Roberts
International journal of molecular sciences, 2021
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Targeted Delivery of Zinc Pyrithione to Skin Epithelia.
Sean E Mangion, Amy M Holmes, Michael S Roberts
International journal of molecular sciences, 2021
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European journal of translational myology, 2023
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The Influence of Zinc Oxide and Zinc Stearate on the Antimicrobial Activity of Coatings Containing Raspberry and Chokeberry Extracts.
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Molecules (Basel, Switzerland), 2024
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Extracellular synthesis of zinc oxide nanoparticle using seaweeds of gulf of Mannar, India.
Nagarajan S, Arumugam Kuppusamy K
Journal of nanobiotechnology, 2013
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Impact of Dietary Zinc Chloride Hydroxide and Zinc Methionine on the Faecal Microbiota of Healthy Adult Horses and Ponies.
Paßlack N, van Bömmel-Wegmann S, Vahjen W, Zentek J
Journal of equine veterinary science, 2022
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Zinc Phosphate Nanoparticles: A Review on Physical, Chemical, and Biological Synthesis and their Applications.
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Current pharmaceutical biotechnology, 2022
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
Sahebnasagh M, Aksi V, Eslami F, Lashkardoost H, Kasaian J et al.
European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
Sahebnasagh M, Aksi V, Eslami F, Lashkardoost H, Kasaian J et al.
European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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European journal of medical research, 2023
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Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
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→
Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial.
Sahebnasagh M, Aksi V, Eslami F, Lashkardoost H, Kasaian J et al.
European journal of medical research, 2023
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Combating Lead/HFD Neurotoxicity in Rats: The Synergistic Effect of 10-Hydroxydecanoic Acid and Zinc Oxide Nanoparticles.
Saleh SR, Atef E, Maher AM, Ghareeb DA, Sheta E et al.
Biological trace element research, 2026
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A review of inorganic UV filters zinc oxide and titanium ...
Samantha L Schneider, Henry W Lim
Photodermatology, photoimmunology & photomedicine, 2019
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Zinc Borate Hydrolysis.
Schubert DM
Molecules (Basel, Switzerland), 2022
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Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
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Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
→
Safety Assessment of Zinc Salts as Used in Cosmetics.
Scott LN, Fiume M, Zhu J, Bergfeld WF, Belsito DV et al.
International journal of toxicology, 2024
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Co-pyrolysis of sunflower-oil cake with potassium carbonate and zinc oxide using plasma torch to produce bio-fuels.
Shie JL, Chang CC, Chang CY, Tzeng CC, Wu CY et al.
Bioresource technology, 2011
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Zinc Oxide Nanoparticle as a Novel Class of Antifungal Ag...
Qi Sun, Jianmei Li, Tao Le
Journal of agricultural and food chemistry, 2018
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Impacts of Gum Arabic and Polyvinylpyrrolidone (PVP) with Salicylic Acid on Peach Fruit (Prunus persica) Shelf Life.
Taher MA, Lo'ay AA, Gouda M, Limam SA, Abdelkader MFM et al.
Molecules (Basel, Switzerland), 2022
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Preparation of porous antibacterial polyamide 6 (PA6) membrane with zinc oxide (ZnO) nanoparticles selectively localized at the pore walls via reactiv
Tang Q, Wang K, Ren X, Zhang Q, Lei W et al.
The Science of the total environment, 2020
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Zinc Phenolsulfonate.
Tucker R, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
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Sustained release of magnesium and zinc ions synergistica...
Fan Yang, Yijia Xue, Feilong Wang, Danni Guo, Yunjiao He, Xiao Zhao + 4 more
Bioactive materials, 2023
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Spindle-Like Zinc Silicate Nanoparticles Accelerating Innervated and Vascularized Skin Burn Wound Healing.
Zhang H, Ma W, Ma H, Qin C, Chen J et al.
Advanced healthcare materials, 2022
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR