This analysis of 13 clinical trials involving 1,752 women found that evening primrose oil was no more effective at reducing breast pain than placebo, topical NSAIDs, vitamin E, or danazol. The good news: it's safe and didn't cause more side effects than other treatments or placebos.
Researchers reviewed published randomized clinical trials comparing evening primrose oil to placebo or other treatments for breast pain, then combined the results to see what the overall evidence showed.
Funding not disclosed in abstract