Researchers reviewed 28 studies on solid lipid nanoparticles (SLNs)—tiny fat-based delivery vehicles—for eye treatments. The results were promising: SLNs showed up to 12-fold better absorption into the eye, kept drugs active for 24-96 hours (vs. regular eye drops that wash away fast), and increased corneal penetration by up to 287%. They worked for conditions like dry eye, glaucoma, and retinal diseases with no significant toxicity reported.

Scientists searched medical databases from 2010-2024 for studies using SLNs specifically for eye applications, reviewed 28 original studies and 20 patents, and analyzed factors like particle size, drug type, and actual results.

Funding not disclosed in abstract