Review
Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S.
J Ashby, H Tinwell, J Plautz, K Twomey, P A Lefevre
ReviewRegulatory toxicology and pharmacology : RTP2001
Research Facts
Lack of binding to isolated estrogen or androgen receptors, and inactivity in the immature rat uterotrophic assay, of the ultraviolet sunscreen filters Tinosorb M-active and Tinosorb S.
J Ashby, H Tinwell, J Plautz, K Twomey, P A Lefevre
Review · Moderate · 2001
Findings

This 2001 study tested whether Tinosorb M-active and Tinosorb S could act like hormones in the body. Both filters showed no binding to estrogen or androgen receptors, and neither triggered hormone-like responses in animal tests—suggesting they don't have endocrine-disrupting activity.

Design
Review
Evidence
Moderate
Journal
Regulatory toxicology and pharmacology : RTP
Methodology

Researchers used lab tests to see if these sunscreen filters could bind to hormone receptors, then confirmed findings with animal studies. Control chemicals that *should* trigger responses did, validating the test methods.

Funded By

Funding not disclosed in abstract