Review
Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
Vincenzo Bettoli, Stefania Zauli, Alessandro Borghi, Giulia Toni, Michela Ricci, Alberto M Bertoldi + 1 more
ReviewGiornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia2017n=6
Research Facts
Efficacy and safety of a 12-month treatment with a combination of hydroxypinacolone retinoate and retinol glycospheres as maintenance therapy in acne patients after oral isotretinoin.
Vincenzo Bettoli, Stefania Zauli, Alessandro Borghi, Giulia Toni, Michela Ricci, Alberto M Bertoldi + 1 more
Review · Moderate · 2017
Findings

In a small study of 39 acne patients, a gel combining hydroxypinacolone retinoate and encapsulated retinol prevented acne relapse in 85% of people over 12 months after they stopped taking oral isotretinoin (a heavy-duty acne drug). No serious side effects were reported, though this was a limited trial focused on maintenance rather than treating active acne.

Design
Review
Sample
n=6
Evidence
Moderate
Journal
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia
Methodology

Researchers treated 40 patients with moderate acne using oral isotretinoin until their acne cleared, then switched them to a daily gel containing hydroxypinacolone retinoate for a full year to see if it would stop acne from coming back.

Funded By

Funding not disclosed in abstract