Researchers found that catalase (an antioxidant enzyme) combined with blocking a specific microRNA called miR-200c accelerated wound healing in diabetic skin cells and diabetic mice. In cells from diabetic patients with foot ulcers, this combination improved healing markers and reduced harmful free radicals more effectively than either treatment alone.

Scientists tested catalase and miR-200c inhibition in lab-grown skin cells from diabetic patients, compared them to healthy controls, and then applied the treatments topically to diabetic mice with wounds to see if healing improved.

Funding not disclosed in abstract