Case Study
Concentrations of Parabens in Human Breast Tumours
Darbre PD, Aljarrah A, Miller WR, Coldham NG, Sauer MJ, Pope GS
Case StudyJournal of Applied Toxicology2004n=20
Research Facts
Concentrations of Parabens in Human Breast Tumours
Darbre PD, Aljarrah A, Miller WR, Coldham NG, Sauer MJ, Pope GS
Case Study ยท Moderate ยท 2004
Findings

Parabens detected in 18 of 20 human breast tumour tissue samples

Design
Case Study
Sample
n=20
Evidence
Moderate
Journal
Journal of Applied Toxicology
Methodology

This study measured concentrations of parabens in 20 human breast tumour tissue samples using HPLC-MS/MS. Intact parabens โ€” methylparaben, ethylparaben, n-propylparaben, n-butylparaben, and isobutylparaben โ€” were detected in 18 of 20 samples. The presence of intact parabens in breast tissue raised questions about the potential for parabens applied in underarm cosmetics to accumulate in breast tissue. This study is one of the most widely cited in the clean beauty movement, though it does not establish a causal link between parabens and breast cancer.

Funded By

UK Department for Environment, Food and Rural Affairs

๐Ÿง‚Conflict of interest.