RCT
Topical Ectoin Versus Topical Dexpanthenol for Managing Acute Radiodermatitis Associated With Breast Cancer Radiotherapy: A Randomized Double-Blind Study.
Nagwa E Abd Elazim, Sara M Awad, Maha S El-Naggar, Rania H Mohamed
RCTDermatitis : contact, atopic, occupational, drug2023n=25
Research Facts
Topical Ectoin Versus Topical Dexpanthenol for Managing Acute Radiodermatitis Associated With Breast Cancer Radiotherapy: A Randomized Double-Blind Study.
Nagwa E Abd Elazim, Sara M Awad, Maha S El-Naggar, Rania H Mohamed
RCT · Strong · 2023
Findings

Ectoin 7% cream outperformed dexpanthenol 5% cream at preventing radiation burns from breast cancer treatment. People using ectoin experienced significantly less pain and itching by week 2, and both ingredients successfully prevented severe burns—though ectoin kept skin damage milder overall.

Design
RCT
Sample
n=25
Evidence
Strong
Journal
Dermatitis : contact, atopic, occupational, drug
Methodology

50 breast cancer patients were randomly assigned to use either ectoin or dexpanthenol cream twice daily during radiotherapy and for 2 weeks after. Researchers tracked skin damage, symptoms, and quality-of-life impacts weekly in a double-blind study.

Funded By

Funding not disclosed in abstract