Review
Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results.
Anny Fourtanier, Dominique Moyal, Sophie Seité
ReviewPhotodermatology, photoimmunology & photomedicine2008
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Research Facts
Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results.
Anny Fourtanier, Dominique Moyal, Sophie Seité
Review · Moderate · 2008 · Photodermatology, photoimmunology & photomedicine
Findings

Sunscreens with Mexoryl SX provided measurable protection against UV damage across multiple markers: it reduced DNA damage (pyrimidine dimers and p53 buildup), prevented excess skin pigmentation in a dose-dependent way, and protected immune function in the skin. The higher the UVA protection level, the better the pigmentation protection—meaning this ingredient actually delivers on broad-spectrum claims.

Design: Review
Evidence: Moderate
Journal: Photodermatology, photoimmunology & photomedicine
Methodology

Researchers tested Mexoryl SX-containing sunscreens against a range of UV damage in human volunteers and patients, measuring everything from skin pigmentation and DNA damage to immune response and inflammation markers.

Funded By

Funding not disclosed in abstract