RCT
Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study.
Meiyan Gao, Ni Gao, Li Wang, Ting Yao, Huan Jing, Hui Liu + 1 more
RCTJournal of cosmetic dermatology2025n=60
Research Facts
Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study.
Meiyan Gao, Ni Gao, Li Wang, Ting Yao, Huan Jing, Hui Liu + 1 more
RCT · Strong · 2025
Findings

A mask with panthenol, centella asiatica, and bisabolol significantly reduced redness and dark spots after laser treatment compared to saline alone, with visible improvements by day 3 and sustained through day 14. It also boosted skin hydration and strengthened the moisture barrier. No safety concerns were found.

Design
RCT
Sample
n=60
Evidence
Strong
Journal
Journal of cosmetic dermatology
Methodology

60 people who received non-ablative fractional laser treatment were split into two groups—one used the panthenol mask, the other got standard saline. Researchers measured redness, pigmentation, hydration, and moisture loss over 14 days using clinical instruments and imaging.

Funded By

Funding not disclosed in abstract