Epidemiological evidence links phthalate exposure to reproductive abnormalities, respiratory effects, and endocrine disruption in humans

This review summarized the epidemiological evidence linking phthalate exposure to adverse health effects in humans. The authors found growing evidence for associations between phthalate exposure (measured via urinary metabolites) and altered reproductive development in males, decreased semen quality, endometriosis, shortened gestational age, and respiratory effects including asthma. The review noted that personal care products are a significant source of diethyl phthalate (DEP) exposure and that aggregate exposure from multiple sources may exceed safe levels.

NIEHS, EPA