Researchers created a microneedle patch loaded with fucoidan (a seaweed extract) that penetrated deep into skin to fight MRSA infections in mice. The patch delivered zinc ions and hyaluronic acid alongside the fucoidan, which worked together to kill bacteria, reduce inflammation, and speed up wound healing—targeting bacteria even inside cells where antibiotics typically can't reach.

Scientists synthesized nanoparticles containing fucoidan coated with hyaluronic acid, loaded them into microneedle patches, and tested the patches on mice with infected wounds to see if they could deliver the ingredients deep into skin layers and fight resistant bacteria.

Funding not disclosed in abstract