Researchers created a microneedle patch infused with fucoidan (a seaweed extract) and zinc nanoparticles to treat infected wounds caused by drug-resistant bacteria (MRSA). In mouse studies, the patches successfully penetrated skin, delivered the active ingredients deep into the wound layer, killed bacteria, reduced inflammation, and promoted healing—all without systemic antibiotics.

Scientists developed a specialized nanoparticle loaded with fucoidan and coated with hyaluronic acid, embedded it into microneedle patches, and tested the patches on mice with serious MRSA-infected wounds to measure infection control and tissue regeneration.

Funding not disclosed in abstract