Cohort
Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen.
J D Johansen, P J Frosch, C Svedman, K E Andersen, M Bruze, C Pirker + 1 more
CohortContact dermatitis2003
Research Facts
Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen.
J D Johansen, P J Frosch, C Svedman, K E Andersen, M Bruze, C Pirker + 1 more
Cohort ยท Moderate ยท 2003
Findings

Lyral, a common fragrance ingredient, triggered allergic reactions in 89% of people who were already sensitive to it when exposed at normal cosmetic product levels. The study found that even low doses caused reactions in most sensitized individuals, suggesting current usage amounts in beauty products are risky for people with fragrance allergies.

Design
Cohort
Evidence
Moderate
Journal
Contact dermatitis
Methodology

Researchers tested 18 people with known Lyral sensitivity and 7 controls using repeated skin applications of different Lyral concentrations over 4 weeks to see what doses would trigger allergic reactions.

Funded By

Funding not disclosed in abstract