Lyral, a common fragrance ingredient, triggered allergic reactions in 89% of people who were already sensitized to it—even at the low doses typically used in cosmetic products. The study found that 2-3% of eczema patients react to Lyral, and researchers concluded current usage levels are causing new sensitization in the general population. They recommended significantly reducing how much Lyral brands are allowed to use.

Researchers tested 18 people with known Lyral sensitivity and 7 controls using repeated applications of different Lyral concentrations over 4 weeks to see what doses would trigger reactions in real-world conditions.

Funding not disclosed in abstract