Hyaluronidase is an effective emergency treatment for complications from hyaluronic acid fillers—it can reverse serious issues like vascular occlusion and blindness when given immediately at high doses. For less urgent problems like bumps, discoloration, or allergic reactions, lower doses work well. While there aren't many large controlled studies, clinical experience shows hyaluronidase has a good safety profile, though dosage and timing matter significantly.

Researchers reviewed published studies and expert recommendations from medical databases to compile what's known about hyaluronidase treatment for filler complications, including dosing protocols and safety data.

Funding not disclosed in abstract