This review examined how fibroblast growth factor (FGF)—a family of cell signaling proteins with 23 identified subtypes—can help heal diabetic foot ulcers, which are notoriously difficult to treat. Researchers found that certain FGF types (FGF-1, FGF-2, FGF-4, FGF-7, FGF-21, and FGF-23) showed therapeutic promise when applied topically, stimulating new blood vessel formation and fibroblast growth—processes essential for wound repair.

This was a literature review that synthesized recent research on how different FGF subtypes work and their potential applications for treating diabetic foot ulcers. It wasn't a new experimental study, but rather an analysis of existing scientific knowledge.

Funding not disclosed in abstract