Review
Effects and Mechanism of the Leontopodium alpinum Callus Culture Extract on Blue Light Damage in Human Foreskin Fibroblasts.
Xianyao Meng, Miaomiao Guo, Zaijun Geng, Ziqiang Wang, Huirong Zhang, Sunhua Li + 2 more
ReviewMolecules (Basel, Switzerland)2023
Research Facts
Effects and Mechanism of the Leontopodium alpinum Callus Culture Extract on Blue Light Damage in Human Foreskin Fibroblasts.
Xianyao Meng, Miaomiao Guo, Zaijun Geng, Ziqiang Wang, Huirong Zhang, Sunhua Li + 2 more
Review ยท Moderate ยท 2023
Findings

An extract from Leontopodium alpinum (edelweiss) reduced blue light damage in lab-grown skin cells by boosting collagen production and reducing harmful inflammation markers. At concentrations of 10-15 mg/mL, it lowered reactive oxygen species (free radicals) and blocked the cellular pathway that blue light triggers to damage skin.

Design
Review
Evidence
Moderate
Journal
Molecules (Basel, Switzerland)
Methodology

Researchers exposed human skin cells to blue light, then treated some with edelweiss extract to see what changed. They measured collagen, inflammation markers, free radicals, and calcium levels using standard lab techniques.

Funded By

Funding not disclosed in abstract