After 12 weeks of daily use, 45% of participants saw at least one grade of wrinkle improvement, with noticeable reduction in nasolabial folds and increased skin elasticity. Users reported moderate satisfaction, and the cream caused no allergic reactions or changes in skin hydration—though nearly half the group saw no improvement.

20 healthy volunteers applied the cream daily for 12 weeks. Researchers measured wrinkles, fold depth, skin thickness, and elasticity at the start, 6 weeks, and 12 weeks.

Funding not disclosed in abstract