After 12 weeks of daily use, 45% of participants saw at least one grade of wrinkle improvement, and nasolabial folds (those lines between nose and mouth) noticeably reduced in depth and volume. Skin elasticity increased significantly, and no allergic reactions or dryness occurred—though about half the group saw improvements, meaning results aren't guaranteed for everyone.

20 healthy volunteers applied the avocado oil and saffron cream daily for 12 weeks. Researchers measured wrinkles, fold depth, skin elasticity, and other biophysical markers at baseline, 6 weeks, and 12 weeks.

Funding not disclosed in abstract