This review found that Spilanthes acmella has multiple bioactive compounds with diverse medicinal properties—traditionally used to relieve toothaches and increasingly studied for cosmetics, supplements, and healthcare applications. The plant showed enough promise across different studies to warrant further development, though the abstract doesn't specify which particular benefits had the strongest evidence.

This is a literature review that analyzed existing research on Spilanthes acmella's chemistry, bioactive compounds, and pharmacological effects rather than conducting new experiments.

Funding not disclosed in abstract