RCT
Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment.
Rosario Russo, Fabiana Superti, Eugen Karadja, Francesco De Seta
RCTMycoses2019
Research Facts
Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment.
Rosario Russo, Fabiana Superti, Eugen Karadja, Francesco De Seta
RCT · Strong · 2019
Findings

When women with recurrent yeast infections took probiotics plus lactoferrin alongside standard antifungal treatment, they had significantly fewer infections come back: only 29% had recurrences after 6 months, compared to 100% in the placebo group. They also reported less itching and discharge at the 3 and 6-month marks.

Design
RCT
Evidence
Strong
Journal
Mycoses
Methodology

48 women with documented recurrent yeast infections were split into two groups—one received probiotics (specific Lactobacillus strains) plus bovine lactoferrin, the other got placebo. Both groups used standard antifungal cream, then continued their assigned treatment for 6 months to track recurrence rates.

Funded By

Funding not disclosed in abstract