RCT
Enhancement of the functionality of women with knee osteoarthritis by a gel formulation with Caryocar coriaceum Wittm ("Pequi") nanoencapsulated pulp fixed oil.
Rodrigo de Faro Silva, André Sales Barreto, Gabriela das Graças Gomes Trindade, Cláudio Moreira Lima, Adriano Antunes de Souza Araújo, Irwin Rose Alencar Menezes + 7 more
RCTBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022
Research Facts
Enhancement of the functionality of women with knee osteoarthritis by a gel formulation with Caryocar coriaceum Wittm ("Pequi") nanoencapsulated pulp fixed oil.
Rodrigo de Faro Silva, André Sales Barreto, Gabriela das Graças Gomes Trindade, Cláudio Moreira Lima, Adriano Antunes de Souza Araújo, Irwin Rose Alencar Menezes + 7 more
RCT · Strong · 2022
Findings

In a clinical trial with women who had knee osteoarthritis, a gel containing nanoencapsulated pequi oil improved knee muscle strength and range of motion, while reducing pain, swelling, and instability. The formulation was safe with no skin irritation or toxicity concerns.

Design
RCT
Evidence
Strong
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Methodology

Researchers created a pequi oil gel formulation and tested it in two stages: first checking its safety and stability in the lab, then running a double-blind randomized trial with women experiencing knee osteoarthritis symptoms.

Funded By

Funding not disclosed in abstract