In lab tests on human skin cells, Hexapeptide-11 activated the cell's natural cleanup and protection systems (proteasome, autophagy, antioxidants) without toxicity. In human subjects, it improved skin elasticity—though the study didn't measure wrinkles or other visible aging signs directly.

Researchers exposed human skin and lung fibroblasts to Hexapeptide-11 in the lab to measure cellular responses, then tested it on human skin in vivo to assess elasticity changes.

Funding not disclosed in abstract