When applied twice daily for 6 weeks, Argireline improved skin structure in aged mice by increasing type I collagen (the stronger, more stable kind) and decreasing type III collagen (the weaker kind). The skin tissue showed visible rejuvenation under the microscope. This suggests Argireline may help with existing wrinkles and prevent new ones from forming.

Researchers applied Argireline to aging mice for 6 weeks and examined skin tissue samples under a microscope to measure collagen changes. This is animal testing, not human testing.

Funding not disclosed in abstract