In aged mice, Argireline applied twice daily for 6 weeks improved skin structure and increased type I collagen (the stronger, more supportive kind) by a statistically significant amount. Type III collagen decreased, which suggests a shift toward healthier, more resilient skin. This is lab work in mice, not humans, so real-world results may differ.

Researchers applied Argireline to aging mice for 6 weeks and examined skin tissue under a microscope to measure changes in collagen types and overall skin structure.

Funding not disclosed in abstract