A small study of 13 people with neck wrinkles found that a single injection of hyaluronic acid mixed with L-carnosine improved wrinkle appearance within one month, with results holding steady at three months. About 85% of participants were satisfied with the results, and side effects were minimal beyond typical injection reactions.

Researchers injected 13 patients with horizontal neck wrinkles using a hyaluronic acid filler containing L-carnosine and tracked their results over three months. Doctors rated wrinkle improvement on a standardized scale, and patients reported their own satisfaction levels.

Funding not disclosed in abstract