In a small study of 13 people with neck wrinkles, a single injection of hyaluronic acid mixed with L-carnosine (an antioxidant) improved wrinkle depth by at least one grade within a month, with results holding steady at three months. 85% of patients were satisfied with the results, and side effects were minimal beyond typical injection reactions.

Researchers injected 13 patients with horizontal neck wrinkles using a hyaluronic acid filler containing L-carnosine and tracked changes in wrinkle severity using a standardized scale for three months.

Funding not disclosed in abstract