Review
The effects of L-tartaric acid on diabetic cataracts through modulation of oxidative stress and inflammation in diabetic rats.
Shengyu Wang, Li Meng, Hengmin Yang
ReviewBMC ophthalmology2025
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Research Facts
The effects of L-tartaric acid on diabetic cataracts through modulation of oxidative stress and inflammation in diabetic rats.
Shengyu Wang, Li Meng, Hengmin Yang
Review · Moderate · 2025 · BMC ophthalmology
Findings

In diabetic rats, L-tartaric acid reduced cataract formation by 62.5%—dropping advanced cataracts from 80% to 30% of cases. It worked by lowering oxidative stress and inflammation in the lens, not by controlling blood sugar. This suggests tartaric acid could potentially help protect eyes in people with diabetes, though human studies are needed.

Design: Review
Evidence: Moderate
Journal: BMC ophthalmology
Methodology

Researchers gave diabetic rats either L-tartaric acid or a placebo daily for 12 weeks, then measured cataract development and tested lens tissue for oxidative damage and inflammatory markers.

Funded By

Funding not disclosed in abstract

The effects of L-tartaric acid on diabetic cataracts through modulation of oxidative stress and inflammation in diabetic rats. — Duck Heart Ghost