Review
Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy.
Katarzyna Witkowska, Magdalena Paczkowska-Walendowska, Ewa Garbiec, Judyta Cielecka-Piontek
ReviewPharmaceutics2024
Research Facts
Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy.
Katarzyna Witkowska, Magdalena Paczkowska-Walendowska, Ewa Garbiec, Judyta Cielecka-Piontek
Review · Moderate · 2024
Findings

Centella asiatica (gotu kola) contains compounds like asiaticoside and madecassoside that boost collagen production, reduce inflammation, and protect skin from oxidative stress. When delivered through advanced formulas like hydrogels and nanostructures, it showed measurable improvements in wound healing speed and size reduction across multiple wound types, including diabetic ulcers and burns—though specific healing timelines weren't detailed in this review.

Design
Review
Evidence
Moderate
Journal
Pharmaceutics
Methodology

This was a literature review that collected and analyzed existing clinical trials on centella asiatica's topical wound-healing effects, synthesizing findings about its active compounds and modern delivery systems rather than conducting new experiments.

Funded By

Funding not disclosed in abstract