RCT
A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy.
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong + 2 more
RCTScientific reports2025n=377
Research Facts
A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy.
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong + 2 more
RCT ยท Strong ยท 2025
Findings

Sea buckthorn oil suppositories improved vaginal tissue health and the quality of colposcopy images in postmenopausal women when used for 2 weeks before the procedure. Results were comparable to prescription estrogen ointment, with both treatments significantly outperforming no pretreatment in reducing bleeding and improving visualization.

Design
RCT
Sample
n=377
Evidence
Strong
Journal
Scientific reports
Methodology

Researchers randomly assigned 368 postmenopausal women undergoing colposcopy into three groups: untreated controls, sea buckthorn oil users, and estrogen ointment users. The oil and ointment groups were treated for 2 weeks before the procedure, then colposcopy results and side effects were compared across all groups.

Funded By

Funding not disclosed in abstract