RCT
A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy.
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong + 2 more
RCTScientific reports2025n=377
Research Facts
A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy.
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong + 2 more
RCT · Strong · 2025
Findings

In postmenopausal women undergoing cervical screening, sea buckthorn oil suppositories used for 2 weeks improved vaginal tissue integrity and imaging quality compared to no treatment—performing similarly to prescription estrogen ointment. The improvement made the screening procedure easier to perform and more satisfactory, though this study focused on procedural outcomes, not treating cervical conditions themselves.

Design
RCT
Sample
n=377
Evidence
Strong
Journal
Scientific reports
Methodology

Researchers gave 368 postmenopausal women either sea buckthorn oil suppositories, estrogen ointment, or no treatment for 2 weeks before cervical colposcopy, then compared how well the screening procedure went across the three groups.

Funded By

Funding not disclosed in abstract