Diethyl Succinate
AKA “123-25-1, Diethyl butanedioate, Ethyl succinate, Butanedioic acid, diethyl ester, Succinic acid diethyl ester, 1, 4-diethyl butanedioate, 4-diethyl ester, Succinic acid, FEMA No. 2377”
Emollient
Ingredient Facts
Diethyl succinate
AKA: 123-25-1, Diethyl butanedioate, Butanedioic acid, Diethyl ester, Succinic acid diethyl ester, 1, 4-diethyl butanedioate, 4-diethyl ester, Succinic acid, FEMA No. 2377
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Solvent
Skin Conditioner
Clean
Diethyl succinate has been reported in Opuntia ficus-indica, Couroupita guianensis, and other organisms with data available.
Solubility 19.1 mg/mL at 25 °C
Formula
C8H14O4
Mol. Weight
174.19
CAS #
123-25-1
Form
Liquid
State
Colorless liquid; [ICSC]
See origin →
Functions
Plasticiser
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Locks In Moisture
Traditional Use
Modern synthetic ester used as a solvent and humectant in cosmetic formulations. Developed to improve product texture and moisture retention in skincare products.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
RIFM fragrance ingredient safety assessment diethyl succinate, CAS Registry Number 123-25-1.
Api AM, Belsito D, Botelho D, Browne D, Bruze M et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018
RIFM fragrance ingredient safety assessment Dimethyl succinate, CAS Registry Number 106-65-0.
Api AM, Belsito D, Botelho D, Browne D, Bruze M et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018
1,4-Butanediol/Succinic Acid/Adipic Acid/HDI Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diethyl Succinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dimethyl Succinate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Succinic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Diethyl Succinate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Dimethyl Succinate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Succinic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR